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Elevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomas
BACKGROUND: Sodium/hydrogen exchanger 1 (NHE1), encoded by the SLC9A1 gene (SoLute Carrier family 9A1) in humans, is the main H(+) efflux mechanism in maintaining alkaline intracellular pH (pH(i)) and Warburg effects in glioma. However, to date, there are no clinical studies exploring pharmacologica...
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| 出版年: | J Exp Clin Cancer Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6192309/ https://ncbi.nlm.nih.gov/pubmed/30333031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0923-z |
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