Upregulation of miR-196b-5p attenuates BCG uptake via targeting SOCS3 and activating STAT3 in macrophages from patients with long-term cigarette smoking-related active pulmonary tuberculosis

BACKGROUND: Cigarette smoking (CS) triggers an intense and harmful inflammatory response in lungs mediated by alveolar and blood macrophages, monocytes, and neutrophils and is closely associated with prevalence of tuberculosis (TB). The risk of death in patients with long-term cigarette smoking-rela...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Yuan, Yaoqin, Lin, Dongzi, Feng, Long, Huang, Mingyuan, Yan, Huimin, Li, Yumei, Chen, Yinwen, Lin, Bihua, Ma, Yan, Ye, Ziyu, Mei, Yuezhi, Yu, Xiaolin, Zhou, Keyuan, Zhang, Qunzhou, Chen, Tao, Zeng, Jincheng
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192289/
https://ncbi.nlm.nih.gov/pubmed/30326918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1654-9
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