Mitochondrial Morphology, Function and Homeostasis Are Impaired by Expression of an N-terminal Calpain Cleavage Fragment of Ataxin-3

Alterations in mitochondrial morphology and function have been linked to neurodegenerative diseases, including Parkinson disease, Alzheimer disease and Huntington disease. Metabolic defects, resulting from dysfunctional mitochondria, have been reported in patients and respective animal models of all...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Harmuth, Tina, Prell-Schicker, Caroline, Weber, Jonasz J., Gellerich, Frank, Funke, Claudia, Drießen, Stefan, Magg, Janine C. D., Krebiehl, Guido, Wolburg, Hartwig, Hayer, Stefanie N., Hauser, Stefan, Krüger, Rejko, Schöls, Ludger, Riess, Olaf, Hübener-Schmid, Jeannette
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192284/
https://ncbi.nlm.nih.gov/pubmed/30364204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00368
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