Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations

Leucine-rich repeat kinase 2 (LRRK2) is the most common causative gene for autosomal dominant Parkinson’s disease (PD) and is also known to be a susceptibility gene for sporadic PD. Although clinical symptoms with LRRK2 mutations are similar to those in sporadic PD, their pathologies are heterogeneo...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Acta Neuropathol Commun
Hlavní autoři: Takanashi, Masashi, Funayama, Manabu, Matsuura, Eiji, Yoshino, Hiroyo, Li, Yuanzhe, Tsuyama, Sho, Takashima, Hiroshi, Nishioka, Kenya, Hattori, Nobutaka
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192197/
https://ncbi.nlm.nih.gov/pubmed/30333048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0617-y
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky