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Owl monkey CCR5 reveals synergism between CD4 and CCR5 in HIV-1 entry

Studying HIV-1 replication in the presence of functionally related proteins from different species has helped define host determinants of HIV-1 infection. Humans and owl monkeys, but not macaques, encode a CD4 receptor that permits entry of transmissible HIV-1 variants due to a single residue differ...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Nahabedian, John, Sharma, Amit, Kaczmarek, Maryska E., Wilkerson, Greg K., Sawyer, Sara L., Overbaugh, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6191650/
https://ncbi.nlm.nih.gov/pubmed/28972927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.09.018
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