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Intracellular trafficking of diphtheria toxin and its mutated form, CRM197, in the endocytic pathway

OBJECTIVE: Diphtheria toxin (DTx) is a well-characterized bacterial toxin. However, the endocytic pathway of the mutant of DTx, CRM197, which is used as an immunological adjuvant, has not yet been fully explained. The aim of this study was to investigate the intracellular trafficking of CRM197-loade...

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Publicado en:North Clin Istanb
Autores principales: Edis, Bilge Ozerman, Haciosmanoglu, Ebru, Varol, Basak, Bektas, Muhammet
Formato: Artigo
Lenguaje:Inglês
Publicado: Kare Publishing 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6191554/
https://ncbi.nlm.nih.gov/pubmed/30374472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14744/nci.2017.55798
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