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Genetics and sex influence peripheral and central innate immune responses and blood-brain barrier integrity

Lipopolysaccharide (LPS) is a stimulator of the innate immune system and is routinely used in animal models to study blood-brain barrier (BBB) dysfunction under inflammatory conditions. It is appreciated that both humans and mice have sexually dimorphic immune responses, which could influence the br...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Erickson, Michelle A., Liang, W. Sandy, Fernandez, Elizabeth G., Bullock, Kristin M., Thysell, Jarl A., Banks, William A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6191122/
https://ncbi.nlm.nih.gov/pubmed/30325961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205769
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