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Intraneuronal protein aggregation as a trigger for inflammation and neurodegeneration in the aging brain
Age is, by far, the greatest risk factor for Alzheimer's disease (AD), yet few AD drug candidates have been generated that target pathways specifically associated with the aging process itself. Two ubiquitous features of the aging brain are the intracellular accumulation of aggregated proteins...
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| Publicado no: | FASEB J |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6191004/ https://ncbi.nlm.nih.gov/pubmed/28049155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601184 |
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