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Predictive biomarkers for tumor immune checkpoint blockade

The development of immune checkpoint inhibitors represented by PD-1 and PD-L1 has provided new hope for the treatment of advanced cancer patients. However, there are no effective predictive biomarkers, which have caused many limitations to the clinical application of immune checkpoint inhibitors. Th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Manag Res
Hauptverfasser: Tong, Mengting, Wang, Jing, He, Wenting, Wang, Yanling, Pan, Hongming, Li, Da, Zhang, Hongliang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190817/
https://ncbi.nlm.nih.gov/pubmed/30349382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S179680
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