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Preparation, Biochemical Analysis, and Structure Determination of Methyllysine Readers

In-depth in vitro characterization of methyllysine reader domains and their association with cognate methyllysine substrates is essential to better understand fundamental mechanisms of chromatin regulation and to design targeted therapeutics that disrupt these interactions. In this chapter, we summa...

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Библиографические подробности
Опубликовано в: :Methods Enzymol
Главные авторы: Musselman, C.A., Kutateladze, T.G.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190708/
https://ncbi.nlm.nih.gov/pubmed/27372761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.12.005
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