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Preparation, Biochemical Analysis, and Structure Determination of Methyllysine Readers

In-depth in vitro characterization of methyllysine reader domains and their association with cognate methyllysine substrates is essential to better understand fundamental mechanisms of chromatin regulation and to design targeted therapeutics that disrupt these interactions. In this chapter, we summa...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Musselman, C.A., Kutateladze, T.G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190708/
https://ncbi.nlm.nih.gov/pubmed/27372761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.12.005
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