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Preparation, Biochemical Analysis, and Structure Determination of Methyllysine Readers

In-depth in vitro characterization of methyllysine reader domains and their association with cognate methyllysine substrates is essential to better understand fundamental mechanisms of chromatin regulation and to design targeted therapeutics that disrupt these interactions. In this chapter, we summa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Methods Enzymol
Hauptverfasser: Musselman, C.A., Kutateladze, T.G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190708/
https://ncbi.nlm.nih.gov/pubmed/27372761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.12.005
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