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Preparation, Biochemical Analysis, and Structure Determination of Methyllysine Readers

In-depth in vitro characterization of methyllysine reader domains and their association with cognate methyllysine substrates is essential to better understand fundamental mechanisms of chromatin regulation and to design targeted therapeutics that disrupt these interactions. In this chapter, we summa...

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Dettagli Bibliografici
Pubblicato in:Methods Enzymol
Autori principali: Musselman, C.A., Kutateladze, T.G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190708/
https://ncbi.nlm.nih.gov/pubmed/27372761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.12.005
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