OKN-007 Decreases Tumor Necrosis and Tumor Cell Proliferation and Increases Apoptosis in a Preclinical F98 Rat Glioma Model

BACKGROUND: Glioblastoma is a malignant World Health Organization (WHO) grade IV glioma with a poor prognosis in humans. New therapeutics are desperately required. The nitrone OKN-007 (2,4-disulfophenyl-PBN) has demonstrated effective anti-glioma properties in several rodent models and is currently...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Magn Reson Imaging
Autori principali: de Souza, Patricia Coutinho, Balasubramanian, Krithika, Njoku, Charity, Smith, Natalyia, Gillespie, David L., Schwager, Andrea, Abdullah, Osama, Ritchey, Jerry W., Fung, Kar-Ming, Saunders, Debra, Jensen, Randy L., Towner, Rheal A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190608/
https://ncbi.nlm.nih.gov/pubmed/25920494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmri.24935
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi