Development and validation of a triplex quantitative real-time PCR assay to detect efflux pump-mediated antibiotic resistance in Burkholderia pseudomallei

AIM: To develop a probe-based triplex quantitative real-time PCR assay to simultaneously detect the upregulation of the efflux pumps AmrAB–OprA, BpeAB–OprB and BpeEF–OprC in Burkholderia pseudomallei strains exhibiting increased minimum inhibitory concentrations toward meropenem, doxycycline or trim...

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Detalhes bibliográficos
Publicado no:Future Microbiol
Main Authors: Webb, Jessica R, Price, Erin P, Somprasong, Nawarat, Schweizer, Herbert P, Baird, Robert W, Currie, Bart J, Sarovich, Derek S
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190177/
https://ncbi.nlm.nih.gov/pubmed/30256166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb-2018-0155
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