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Impedance-based analysis of mu opioid receptor signaling and underlying mechanisms

The mu opioid receptor is a G-protein coupled receptor able to signal through the Gα(i)(/o) class of G-protein and β-arrestin pathways, stimulating down-stream effector pathways. Signaling bias occurs when different receptor agonists lead to different signaling outcomes. Traditionally these have bee...

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Publicado en:Biochem Biophys Rep
Autor principal: Thirkettle-Watts, David
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189789/
https://ncbi.nlm.nih.gov/pubmed/30338303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.03.002
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