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Wt1 dictates the fate of fetal and adult Leydig cells during development in the mouse testis
Wilms' tumor 1 (Wt1) is a tumor suppressor gene encoding ∼24 zinc finger transcription factors. In the mammalian testis, Wt1 is expressed mostly by Sertoli cells (SCs) involved in testis development, spermatogenesis, and adult Leydig cell (ALC) steroidogenesis. Global knockout (KO) of Wt1 is le...
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| Publicado no: | Am J Physiol Endocrinol Metab |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6189632/ https://ncbi.nlm.nih.gov/pubmed/25336526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00425.2014 |
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