Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation

Sertoli and Leydig cells, the two major somatic cell types in the testis, have different morphologies and functions. Both are essential for gonad development and spermatogenesis. However, whether these cells are derived from the same progenitor cells and the mechanism regulating the differentiation...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Zhang, Lianjun, Chen, Min, Wen, Qing, Li, Yaqiong, Wang, Yaqing, Wang, Yanbo, Qin, Yan, Cui, Xiuhong, Yang, Lin, Huff, Vicki, Gao, Fei
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386376/
https://ncbi.nlm.nih.gov/pubmed/25775596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422371112
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