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In Situ Structures of the Polymerase Complex and RNA Genome Show How Aquareovirus Transcription Machineries Respond to Uncoating

Reoviruses carry out genomic RNA transcription within intact viruses to synthesize plus-sense RNA strands, which are capped prior to their release as mRNA. The in situ structures of the transcriptional enzyme complex (TEC) containing the RNA-dependent RNA polymerase (RdRp) and NTPase are known for t...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Ding, Ke, Nguyen, Lisa, Zhou, Z. Hong
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189512/
https://ncbi.nlm.nih.gov/pubmed/30068643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00774-18
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