Acute-Phase CD4(+) T Cell Responses Targeting Invariant Viral Regions Are Associated with Control of Live Attenuated Simian Immunodeficiency Virus

We manipulated SIVmac239Δnef, a model of major histocompatibility complex (MHC)-independent viral control, to evaluate characteristics of effective cellular responses mounted by Mauritian cynomolgus macaques (MCMs) that express the M3 MHC haplotype, which has been associated with poor control of pat...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Sutton, Matthew S., Ellis-Connell, Amy, Moriarty, Ryan V., Balgeman, Alexis J., Gellerup, Dane, Barry, Gabrielle, Weiler, Andrea M., Friedrich, Thomas C., O'Connor, Shelby L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189504/
https://ncbi.nlm.nih.gov/pubmed/30111562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00830-18
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