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Decreased c-Myc mRNA Stability via the MicroRNA 141-3p/AUF1 Axis Is Crucial for p63α Inhibition of Cyclin D1 Gene Transcription and Bladder Cancer Cell Tumorigenicity

Bladder cancer (BC) ranks as the sixth most common cancer in the United States and is the leading cause of death in patients with urinary malignancies. p63 is a member of the p53 family and is believed to function as a tumor suppressor in human BCs. Our most recent studies revealed a previously unkn...

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Библиографические подробности
Опубликовано в: :Mol Cell Biol
Главные авторы: Li, Xin, Tian, Zhongxian, Jin, Honglei, Xu, Jiheng, Hua, Xiaohui, Yan, Huiying, Liufu, Huating, Wang, Jingjing, Li, Jingxia, Zhu, Junlan, Huang, Haishan, Huang, Chuanshu
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189456/
https://ncbi.nlm.nih.gov/pubmed/30104251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00273-18
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