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Yes-associated protein promotes the abnormal proliferation of psoriatic keratinocytes via an amphiregulin dependent pathway

Psoriasis is a chronic inflammatory skin disease with high morbidity, poor treatment methods and high rates of relapse. Keratinocyte hyperproliferation and shortened cell cycles are important pathophysiological features of psoriasis. As a known oncogene, Yes-associated protein (YAP) plays a role in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jia, Jinjing, Li, Changji, Yang, Jiao, Wang, Xin, Li, Ruilian, Luo, Suju, Li, Zhengxiao, Liu, Jiankang, Liu, Zhi, Zheng, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189173/
https://ncbi.nlm.nih.gov/pubmed/30323299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32522-y
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