Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin

Whether non-integrated viral DNAs distribute randomly or target specific positions within the higher-order architecture of mammalian genomes remains largely unknown. Here we use Hi-C and viral DNA capture (CHi-C) in primary human hepatocytes infected by either hepatitis B virus (HBV) or adenovirus t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Moreau, Pierrick, Cournac, Axel, Palumbo, Gianna Aurora, Marbouty, Martial, Mortaza, Shogofa, Thierry, Agnes, Cairo, Stefano, Lavigne, Marc, Koszul, Romain, Neuveut, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189100/
https://ncbi.nlm.nih.gov/pubmed/30323189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06739-4
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