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BRAF and MEK inhibitor therapy eliminates nestin expressing melanoma cells in human tumors

Little is known about the in vivo impacts of targeted therapy on melanoma cell abundance and protein expression. Here, 21 antibodies were added to an established melanoma mass cytometry panel to measure 32 cellular features, distinguish malignant cells, and characterize dabrafenib and trametinib res...

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Detalhes bibliográficos
Publicado no:Pigment Cell Melanoma Res
Main Authors: Doxie, Deon B., Greenplate, Allison R., Gandelman, Jocelyn S., Diggins, Kirsten E., Roe, Caroline E., Dahlman, Kimberly B., Sosman, Jeffrey A., Kelley, Mark C., Irish, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188784/
https://ncbi.nlm.nih.gov/pubmed/29778085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12712
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