Orchestrated regulation of iron trafficking proteins in the kidney during iron overload facilitates systemic iron retention

The exact route of iron through the kidney and its regulation during iron overload are not completely elucidated. Under physiologic conditions, non-transferrin and transferrin bound iron passes the glomerular filter and is reabsorbed through kidney epithelial cells, so that hardly any iron is found...

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Veröffentlicht in:PLoS One
Hauptverfasser: Weiss, Avital, Spektor, Lior, A. Cohen, Lyora, Lifshitz, Lena, Magid Gold, Inbar, Zhang, De-Liang, Truman-Rosentsvit, Marianna, Leichtmann-Bardoogo, Yael, Nyska, Abraham, Addadi, Sefi, Rouault, Tracey A., Meyron-Holtz, Esther G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188744/
https://ncbi.nlm.nih.gov/pubmed/30321179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204471
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