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Mechanisms of the anti-aging and prolongevity effects of caloric restriction: evidence from studies of genetically modified animals
It is widely accepted that caloric restriction (CR) extends lifespan and suppresses various pathophysiological changes. CR suppresses growth hormone/insulin-like growth factor signaling and mechanistic target of rapamycin complex 1 activity, activates sirtuin and enhances mitochondrial redox regulat...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6188494/ https://ncbi.nlm.nih.gov/pubmed/30222593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101557 |
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