Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction

Caloric restriction (CR) is the most potent intervention known to both protect against carcinogenesis and extend lifespan in laboratory animals. A variety of anticarcinogens and CR mimetics induce and activate the NF-E2-related factor 2 (Nrf2) pathway. Nrf2, in turn, induces a number of antioxidativ...

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Detaylı Bibliyografya
Asıl Yazarlar: Pearson, Kevin J., Lewis, Kaitlyn N., Price, Nathan L., Chang, Joy W., Perez, Evelyn, Cascajo, Maria Victoria, Tamashiro, Kellie L., Poosala, Suresh, Csiszar, Anna, Ungvari, Zoltan, Kensler, Thomas W., Yamamoto, Masayuki, Egan, Josephine M., Longo, Dan L., Ingram, Donald K., Navas, Placido, de Cabo, Rafael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268135/
https://ncbi.nlm.nih.gov/pubmed/18287083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712162105
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