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Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels

BACKGROUND: Tumor vessels were persistently compressed by solid stress from tumor interstitial matrix, resulting in limited vessel perfusion and oxygen concentrations. Collagen within matrix participated in transmitting the solid stress to tumor vessels and limiting drug delivery. PURPOSE: The objec...

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Опубликовано в: :Int J Nanomedicine
Главные авторы: Zhao, Xiaoxu, Pan, Jinghua, Li, Wei, Yang, Wende, Qin, Li, Pan, Yunlong
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188185/
https://ncbi.nlm.nih.gov/pubmed/30349245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S176928
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