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Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels

BACKGROUND: Tumor vessels were persistently compressed by solid stress from tumor interstitial matrix, resulting in limited vessel perfusion and oxygen concentrations. Collagen within matrix participated in transmitting the solid stress to tumor vessels and limiting drug delivery. PURPOSE: The objec...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Nanomedicine
Main Authors: Zhao, Xiaoxu, Pan, Jinghua, Li, Wei, Yang, Wende, Qin, Li, Pan, Yunlong
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188185/
https://ncbi.nlm.nih.gov/pubmed/30349245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S176928
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