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Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels

BACKGROUND: Tumor vessels were persistently compressed by solid stress from tumor interstitial matrix, resulting in limited vessel perfusion and oxygen concentrations. Collagen within matrix participated in transmitting the solid stress to tumor vessels and limiting drug delivery. PURPOSE: The objec...

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Bibliografische gegevens
Gepubliceerd in:Int J Nanomedicine
Hoofdauteurs: Zhao, Xiaoxu, Pan, Jinghua, Li, Wei, Yang, Wende, Qin, Li, Pan, Yunlong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188185/
https://ncbi.nlm.nih.gov/pubmed/30349245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S176928
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