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In situ misemgel as a multifunctional dual-absorption platform for nasal delivery of raloxifene hydrochloride: formulation, characterization, and in vivo performance

BACKGROUND: Raloxifene hydrochloride (RLX) is approved by the US Food and Drug Administration for the treatment and prevention of osteoporosis, in addition to reducing the risk of breast cancer in postmenopausal women. RLX has the disadvantages of low aqueous solubility, extensive presystemic intest...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Ahmed, Osama AA, Badr-Eldin, Shaimaa M
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188068/
https://ncbi.nlm.nih.gov/pubmed/30349253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S181587
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