Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity

In this report, we present a case study of how pharmacogenomics and pharmacometabolomics can be useful to characterize safety and pharmacokinetic profiles in early phase new drug development clinical trials. During conducting a first-in-human trial for a new molecular entity, we were able to determi...

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Publicado en:Genomics Inform
Autores principales: Oh, Jaeseong, Yi, Sojeong, Gu, Namyi, Shin, Dongseong, Yu, Kyung-Sang, Yoon, Seo Hyun, Cho, Joo-Youn, Jang, In-Jin
Formato: Artigo
Lenguaje:Inglês
Publicado: Society of Gastrointestinal Intervention 2018
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187817/
https://ncbi.nlm.nih.gov/pubmed/30309203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5808/GI.2018.16.3.52
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