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Stimulation of AMPK prevents degeneration of photoreceptors and the retinal pigment epithelium

Retinal degenerative diseases are generally characterized by a permanent loss of light-sensitive retinal neurons known as photoreceptors, or their support cells, the retinal pigmented epithelium (RPE). Metabolic dysfunction has been implicated as a common mechanism of degeneration. In this study, we...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Xu, Lei, Kong, Li, Wang, Jiangang, Ash, John D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187182/
https://ncbi.nlm.nih.gov/pubmed/30249643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802724115
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