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ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB
The protein disaggregase ClpB hexamer is conserved across evolution and has two AAA+-type nucleotide-binding domains, NBD1 and NBD2, in each protomer. In M. tuberculosis (Mtb), ClpB facilitates asymmetric distribution of protein aggregates during cell division to help the pathogen survive and persis...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6187150/ https://ncbi.nlm.nih.gov/pubmed/30257943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1810648115 |
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