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The effect of combined treatment with sodium phenylbutyrate and cisplatin, erlotinib, or gefitinib on resistant NSCLC cells

BACKGROUND: Chemotherapy resistance is the main cause of the marginal clinical benefit of platinum-based chemotherapy and tyrosine kinase inhibitors in advanced non-small-cell lung cancer (NSCLC). Thus, the identification of new therapeutic agents that can enhance the sensitivity of these drugs is o...

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Pubblicato in:Clin Pharmacol
Autori principali: Al-Keilani, Maha S, Alzoubi, Karem H, Jaradat, Saied A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186900/
https://ncbi.nlm.nih.gov/pubmed/30349406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S174074
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