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Combined treatment with N‐acetylcysteine and gefitinib overcomes drug resistance to gefitinib in NSCLC cell line

We aimed to explore the molecular substrate underlying EGFR‐TKI resistance and investigate the effects of N‐acetylcysteine (NAC) on reversing EGFR‐TKI resistance. In the current research, the effects of NAC in combination with gefitinib on reversing gefitinib resistance were examined using CCK‐8 ass...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Li, Jun, Wang, Xiao‐Hui, Hu, Jing, Shi, Meng, Zhang, Lu, Chen, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013061/
https://ncbi.nlm.nih.gov/pubmed/31891230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2610
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