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Perspective: Spectrin-Like Repeats in Dystrophin Have Unique Binding Preferences for Syntrophin Adaptors That Explain the Mystery of How nNOSμ Localizes to the Sarcolemma

Dystrophin is a massive multi-domain protein composed of specialized amino and carboxyl termini that are separated by 24 spectrin-like repeats. Dystrophin performs critical structural and signaling roles that are indispensable for the functional integrity of skeletal muscle. Indeed, the loss of dyst...

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Bibliografske podrobnosti
izdano v:Front Physiol
Glavni avtor: Percival, Justin M.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186803/
https://ncbi.nlm.nih.gov/pubmed/30349485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01369
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