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Evaluation and calibration of high-throughput predictions of chemical distribution to tissues

Toxicokinetics (TK) provides critical information for integrating chemical toxicity and exposure assessments in order to determine potential chemical risk (i.e., the margin between toxic doses and plausible exposures). For thousands of chemicals that are present in our environment, in vivo TK data a...

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Bibliografske podrobnosti
izdano v:J Pharmacokinet Pharmacodyn
Main Authors: Pearce, Robert, Setzer, R. Woodrow, Davis, Jimena, Wambaugh, John F.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186149/
https://ncbi.nlm.nih.gov/pubmed/29032447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-017-9548-7
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