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Predicting variant deleteriousness in non-human species: applying the CADD approach in mouse

BACKGROUND: Predicting the deleteriousness of observed genomic variants has taken a step forward with the introduction of the Combined Annotation Dependent Depletion (CADD) approach, which trains a classifier on the wealth of available human genomic information. This raises the question whether it c...

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Dades bibliogràfiques
Publicat a:BMC Bioinformatics
Autors principals: Groß, Christian, de Ridder, Dick, Reinders, Marcel
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186050/
https://ncbi.nlm.nih.gov/pubmed/30314430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2337-5
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