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Myogenin promotes myocyte fusion to balance fibre number and size

Each skeletal muscle acquires its unique size before birth, when terminally differentiating myocytes fuse to form a defined number of multinucleated myofibres. Although mice in which the transcription factor Myogenin is mutated lack most myogenesis and die perinatally, a specific cell biological rol...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Ganassi, Massimo, Badodi, Sara, Ortuste Quiroga, Huascar Pedro, Zammit, Peter S., Hinits, Yaniv, Hughes, Simon M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185967/
https://ncbi.nlm.nih.gov/pubmed/30315160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06583-6
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