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Probing aggrephagy using chemically-induced protein aggregates

Selective types of autophagy mediate the clearance of specific cellular components and are essential to maintain cellular homeostasis. However, tools to directly induce and monitor such pathways are limited. Here we introduce the PIM (particles induced by multimerization) assay as a tool for the stu...

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Vydáno v:Nat Commun
Hlavní autoři: Janssen, Anne F. J., Katrukha, Eugene A., van Straaten, Wendy, Verlhac, Pauline, Reggiori, Fulvio, Kapitein, Lukas C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185936/
https://ncbi.nlm.nih.gov/pubmed/30315152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06674-4
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