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In vitro transport of methotrexate by Drosophila Multidrug Resistance-associated Protein

Methotrexate (MTX) is a widely used chemotherapeutic agent, immune suppressant and antimalarial drug. It is a substrate of several human ABC proteins that confer multidrug resistance to cancer cells and determine compartmentalization of a wide range of physiological metabolites and endo or xenobioti...

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Publicado en:PLoS One
Autores principales: Karasik, Agnes, Váradi, András, Szeri, Flóra
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185855/
https://ncbi.nlm.nih.gov/pubmed/30312334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205657
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