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HOW DOES THE SILENCING OF THE INFLAMMATION MEDIATOR GENE: FAT10, EXTEND LIFESPAN IN MICE?
FAT10 knockout mice display 50% reduction in total body fat and 20% increase in median and maximal lifespan, in both sexes. It is still unclear how FAT10 silencing affects aging and metabolism. Our current studies provide novel mechanistic insights for the role of this inflammation related gene - FA...
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Publicado no: | Innov Aging |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6185008/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3533 |
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