Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy via genome-wide transcriptome changes

Pediatric glioblastoma (GBM) is a relatively rare brain tumor in children that has a dismal prognosis. Surgery followed by radiotherapy is the main treatment protocol used for older patients. The benefit of adjuvant chemotherapy is still limited due to a poor understanding of the underlying molecula...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Alhajala, Hisham S., Nguyen, Ha S., Shabani, Saman, Best, Benjamin, Kaushal, Mayank, Al-Gizawiy, Mona M., Erin Ahn, Eun-Young, Knipstein, Jeffery A., Mirza, Shama, Schmainda, Kathleen M., Chitambar, Christopher R., Doan, Ninh B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183347/
https://ncbi.nlm.nih.gov/pubmed/30344926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26137
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