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Molecular mechanism of panaxydol on promoting axonal growth in PC12 cells

Nerve growth factor (NGF) promotes axonal growth in PC12 cells primarily by regulating the RTK-RAS-MEK-ERK pathway. Panaxydol, a polyacetylene isolated from Panax notoginseng, can mimic the effects of NGF. Panaxydol promotes neurite outgrowth in PC12 cells, but its molecular mechanism remains unclea...

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Detalhes bibliográficos
Publicado no:Neural Regen Res
Main Authors: Li, Wei-Peng, Ma, Ke, Jiang, Xiao-Yan, Yang, Rui, Lu, Pei-Hua, Nie, Bao-Ming, Lu, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183029/
https://ncbi.nlm.nih.gov/pubmed/30233066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.239439
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