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Diastereoselective C–H carbonylative annulation of aliphatic amines: a rapid route to functionalized γ-lactams

A palladium(ii)-catalysed C(sp(3))–H carbonylation of free(NH) secondary aliphatic amines to 2-pyrrolidinones is described. A correlation between the nature of the carboxylate ligand and the diastereoselectivity and yield of the process was observed. As such, under these optimal conditions a range o...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chem Sci
Egile Nagusiak: Png, Zhuang Mao, Cabrera-Pardo, Jaime R., Peiró Cadahía, Jorge, Gaunt, Matthew J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Royal Society of Chemistry 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182607/
https://ncbi.nlm.nih.gov/pubmed/30393523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02855a
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