Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

PURPOSE: Pre-clinical animal studies precede the majority of clinical trials. While the clinical sepsis definitions and recommended treatments are regularly updated, a systematic review of pre-clinical models of sepsis has not been done and clear modeling guidelines are lacking. To address this defi...

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Bibliographic Details
Published in:Infection
Main Authors: Osuchowski, Marcin F., Ayala, Alfred, Bahrami, Soheyl, Bauer, Michael, Boros, Mihaly, Cavaillon, Jean-Marc, Chaudry, Irshad H., Coopersmith, Craig M., Deutschman, Clifford, Drechsler, Susanne, Efron, Philip, Frostell, Claes, Fritsch, Gerhard, Gozdzik, Waldemar, Hellman, Judith, Huber-Lang, Markus, Inoue, Shigeaki, Knapp, Sylvia, Kozlov, Andrey V., Libert, Claude, Marshall, John C., Moldawer, Lyle L., Radermacher, Peter, Redl, Heinz, Remick, Daniel G., Singer, Mervyn, Thiemermann, Christoph, Wang, Ping, Wiersinga, W. Joost, Xiao, Xianzhong, Zingarelli, Basilia
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2018
Subjects:
Expert Opinion
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182493/
https://ncbi.nlm.nih.gov/pubmed/30105433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s15010-018-1183-8
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