High-grade glioma associated immunosuppression does not prevent immune responses induced by therapeutic vaccines in combination with T(reg) depletion

High-grade gliomas (HGG) exert systemic immunosuppression, which is of particular importance as immunotherapeutic strategies such as therapeutic vaccines are increasingly used to treat HGGs. In a first cohort of 61 HGG patients we evaluated a panel of 30 hematological and 34 plasma biomarkers. Then,...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Löhr, Mario, Freitag, Benjamin, Technau, Antje, Krauss, Jürgen, Monoranu, Camelia-Maria, Rachor, Johannes, Lutz, Manfred B., Hagemann, Carsten, Kessler, Almuth F., Linsenmann, Thomas, Wölfl, Matthias, Ernestus, Ralf-Ingo, Engelhardt, Sabrina, Gelbrich, Götz, Schlegel, Paul G., Eyrich, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182405/
https://ncbi.nlm.nih.gov/pubmed/30054667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-018-2214-0
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