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TLR2 Ligand Pam3CSK4 Regulates MMP-2/9 Expression by MAPK/NF-κB Signaling Pathways in Primary Brain Microvascular Endothelial Cells

Blood–brain barrier (BBB) destruction is associated with a variety of neurological diseases. Brain microvascular endothelial cells (BMECs) are the key constituent of BBB. Both matrix metalloproteinases-2/9 (MMP-2/9) and toll-like receptor-2 (TLR2) are coexpressed in BMECs and have been shown to play...

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Detalhes bibliográficos
Publicado no:Neurochem Res
Main Authors: Zhu, Hongyan, Dai, Rongrong, Zhou, Youquan, Fu, Hao, Meng, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182369/
https://ncbi.nlm.nih.gov/pubmed/30088235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-018-2607-7
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