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The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models

BACKGROUND: Toll-like receptors (TLRs) play an important role in the innate and adaptive immune responses to pathogens, and are the target of new vaccine adjuvants. TLR2 plays a role in parasite recognition and activation of immune responses during cutaneous leishmaniasis infection, suggesting that...

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Detalhes bibliográficos
Publicado no:Parasit Vectors
Main Authors: Halliday, Alice, Turner, Joseph D., Guimarães, Ana, Bates, Paul A., Taylor, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761161/
https://ncbi.nlm.nih.gov/pubmed/26897363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-016-1381-0
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