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A synthetic free fatty acid-regulated transgene switch in mammalian cells and mice

Trigger-inducible transgene expression systems are utilized in biopharmaceutical manufacturing and also to enable controlled release of therapeutic agents in vivo. We considered that free fatty acids (FFAs), which are dietary components, signaling molecules and important biomarkers, would be attract...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Liu, Ying, Charpin-El Hamri, Ghislaine, Ye, Haifeng, Fussenegger, Martin
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182168/
https://ncbi.nlm.nih.gov/pubmed/30219861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky805
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