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A synthetic free fatty acid-regulated transgene switch in mammalian cells and mice
Trigger-inducible transgene expression systems are utilized in biopharmaceutical manufacturing and also to enable controlled release of therapeutic agents in vivo. We considered that free fatty acids (FFAs), which are dietary components, signaling molecules and important biomarkers, would be attract...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6182168/ https://ncbi.nlm.nih.gov/pubmed/30219861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky805 |
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