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A synthetic free fatty acid-regulated transgene switch in mammalian cells and mice

Trigger-inducible transgene expression systems are utilized in biopharmaceutical manufacturing and also to enable controlled release of therapeutic agents in vivo. We considered that free fatty acids (FFAs), which are dietary components, signaling molecules and important biomarkers, would be attract...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Liu, Ying, Charpin-El Hamri, Ghislaine, Ye, Haifeng, Fussenegger, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182168/
https://ncbi.nlm.nih.gov/pubmed/30219861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky805
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