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Self-adjusting synthetic gene circuit for correcting insulin resistance
By using tools from synthetic biology, sophisticated genetic devices can be assembled to reprogram mammalian cell activities. Here, we demonstrate that a self-adjusting synthetic gene circuit can be designed to sense and reverse the insulin-resistance syndrome in different mouse models. By functiona...
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| Опубликовано в: : | Nat Biomed Eng |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5412959/ https://ncbi.nlm.nih.gov/pubmed/28480128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-016-0005 |
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